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Fibroblast to myofibroblast transition is enhanced by increased cell density

Idiopathic pulmonary fibrosis (IPF) is a chronic disease of the lung caused by a rampant inflammatory response that results in the deposition of excessive extracellular matrix (ECM). IPF patient lungs also develop fibroblastic foci that consist of activated fibroblasts and myofibroblasts. In concert...

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Detalles Bibliográficos
Autores principales: Doolin, Mary T., Smith, Ian M., Stroka, Kimberly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694087/
https://www.ncbi.nlm.nih.gov/pubmed/34731044
http://dx.doi.org/10.1091/mbc.E20-08-0536