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Subunit exchange among endolysosomal tethering complexes is linked to contact site formation at the vacuole

The hexameric HOPS (homotypic fusion and protein sorting) complex is a conserved tethering complex at the lysosome-like vacuole, where it mediates tethering and promotes all fusion events involving this organelle. The Vps39 subunit of this complex also engages in a membrane contact site between the...

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Detalles Bibliográficos
Autores principales: González Montoro, Ayelén, Vargas Duarte, Prado, Auffarth, Kathrin, Walter, Stefan, Fröhlich, Florian, Ungermann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694092/
https://www.ncbi.nlm.nih.gov/pubmed/34668759
http://dx.doi.org/10.1091/mbc.E21-05-0227