Molecular Mechanisms Driving the In Vivo Development of KPC-71-Mediated Resistance to Ceftazidime-Avibactam during Treatment of Carbapenem-Resistant Klebsiella pneumoniae Infections

Here, we characterized the mechanisms resulting in the development of KPC-71-mediated resistance to ceftazidime-avibactam (CZA) during treatment of carbapenem-resistant Klebsiella pneumoniae (CRKP) infections. CZA-susceptible and CZA-resistant K. pneumoniae strains, namely, KP357 and KP697, were iso...

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Detalles Bibliográficos
Autores principales: Li, Xi, Ke, Huanhuan, Wu, Wenhao, Tu, Yuexing, Zhou, Hua, Yu, Yunsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694138/
https://www.ncbi.nlm.nih.gov/pubmed/34935448
http://dx.doi.org/10.1128/mSphere.00859-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694138/
https://www.ncbi.nlm.nih.gov/pubmed/34935448
http://dx.doi.org/10.1128/mSphere.00859-21

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