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The Betacoronavirus PHEV Replicates and Disrupts the Respiratory Epithelia and Upregulates Key Pattern Recognition Receptor Genes and Downstream Mediators, Including IL-8 and IFN-λ

The upper respiratory tract is the primary site of infection by porcine hemagglutinating encephalomyelitis virus (PHEV). In this study, primary porcine respiratory epithelial cells (PRECs) were cultured in an air-liquid interface (ALI) to differentiate into a pseudostratified columnar epithelium, pr...

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Detalles Bibliográficos
Autores principales: Nelli, Rahul K., Mora-Díaz, Juan Carlos, Giménez-Lirola, Luis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694173/
https://www.ncbi.nlm.nih.gov/pubmed/34935443
http://dx.doi.org/10.1128/mSphere.00820-21