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Neutrophil-Mediated Lung Injury Both via TLR2-Dependent Production of IL-1α and IL-12 p40, and TLR2-Independent CARDS Toxin after Mycoplasma pneumoniae Infection in Mice

Mycoplasma pneumoniae (Mp) residing extracellularly in the respiratory tract is the primary cause of bacterial community-acquired pneumonia in humans. However, the detailed pathological mechanism of Mp infection, especially inflammation in the lung, remains unclear. This study examined the role of t...

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Detalles Bibliográficos
Autores principales: Tamiya, Shigeyuki, Yoshikawa, Eisuke, Ogura, Monami, Kuroda, Etsushi, Suzuki, Koichiro, Yoshioka, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694186/
https://www.ncbi.nlm.nih.gov/pubmed/34937175
http://dx.doi.org/10.1128/spectrum.01588-21