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EPSP Synthase-Depleted Cells Are Aromatic Amino Acid Auxotrophs in Mycobacterium smegmatis

The epidemiological importance of mycobacterial species is indisputable, and the necessity to find new molecules that can inhibit their growth is urgent. The shikimate pathway, required for the synthesis of important bacterial metabolites, represents a set of targets for inhibitors of Mycobacterium...

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Detalles Bibliográficos
Autores principales: Duque-Villegas, Mario Alejandro, Abbadi, Bruno Lopes, Romero, Paulo Ricardo, Matter, Letícia Beatriz, Galina, Luiza, Dalberto, Pedro Ferrari, Rodrigues-Junior, Valnês da Silva, Ducati, Rodrigo Gay, Roth, Candida Deves, Rambo, Raoní Scheibler, de Souza, Eduardo Vieira, Perello, Marcia Alberton, Morbidoni, Héctor Ricardo, Machado, Pablo, Basso, Luiz Augusto, Bizarro, Cristiano Valim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694188/
https://www.ncbi.nlm.nih.gov/pubmed/34937164
http://dx.doi.org/10.1128/Spectrum.00009-21