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A phase II study of laser interstitial thermal therapy combined with doxorubicin in patients with recurrent glioblastoma

BACKGROUND: The blood-brain barrier (BBB) is a major limiting factor for drug delivery in brain tumors. Laser interstitial thermal therapy (LITT) disrupts the peritumoral BBB. In this study, we examine survival in patients with recurrent glioblastoma (GBM) treated with LITT followed by low-dose doxo...

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Detalles Bibliográficos
Autores principales: Butt, Omar H, Zhou, Alice Y, Huang, Jiayi, Leidig, William A, Silberstein, Alice E, Chheda, Milan G, Johanns, Tanner M, Ansstas, George, Liu, Jingxia, Talcott, Grayson, Nakiwala, Ruth, Shimony, Joshua S, Kim, Albert H, Leuthardt, Eric C, Tran, David D, Campian, Jian L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694207/
https://www.ncbi.nlm.nih.gov/pubmed/34988450
http://dx.doi.org/10.1093/noajnl/vdab164