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Integrative 5-Methylcytosine Modification Immunologically Reprograms Tumor Microenvironment Characterizations and Phenotypes of Clear Cell Renal Cell Carcinoma

The tumor microenvironment (TME) affects the biologic malignancy of clear cell renal cell carcinoma (ccRCC). The influence of the 5-methylcytosine (m(5)C) epigenetic modification on the TME is unknown. We comprehensively assessed m(5)C modification patterns of 860 ccRCC samples (training, testing, a...

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Detalles Bibliográficos
Autores principales: Xu, Wenhao, Zhu, Wenkai, Tian, Xi, Liu, Wangrui, Wu, Yuanyuan, Anwaier, Aihetaimujiang, Su, Jiaqi, Wei, Shiyin, Qu, Yuanyuan, Zhang, Hailiang, Ye, Dingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694268/
https://www.ncbi.nlm.nih.gov/pubmed/34957104
http://dx.doi.org/10.3389/fcell.2021.772436