Employing complementary spectroscopies to study the conformations of an epimeric pair of side-chain stapled peptides in aqueous solution

Understanding the conformational preferences of free ligands in solution is often necessary to rationalize structure–activity relationships in drug discovery. Herein, we examine the conformational behavior of an epimeric pair of side-chain stapled peptides that inhibit the FAD dependent amine oxidas...

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Detalles Bibliográficos
Autores principales: Bogaerts, Jonathan, Atilaw, Yoseph, Peintner, Stefan, Aerts, Roy, Kihlberg, Jan, Johannessen, Christian, Erdélyi, Máté
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694311/
https://www.ncbi.nlm.nih.gov/pubmed/35424346
http://dx.doi.org/10.1039/d0ra10167b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694311/
https://www.ncbi.nlm.nih.gov/pubmed/35424346
http://dx.doi.org/10.1039/d0ra10167b

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