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Rapid and column-free syntheses of acyl fluorides and peptides using ex situ generated thionyl fluoride

Thionyl fluoride (SOF(2)) was first isolated in 1896, but there have been less than 10 subsequent reports of its use as a reagent for organic synthesis. This is partly due to a lack of facile, lab-scale methods for its generation. Herein we report a novel protocol for the ex situ generation of SOF(2...

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Detalles Bibliográficos
Autores principales: Lee, Cayo, Thomson, Brodie J., Sammis, Glenn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694322/
https://www.ncbi.nlm.nih.gov/pubmed/35059166
http://dx.doi.org/10.1039/d1sc05316g