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Mass spectral and theoretical investigations of the transient proton-bound dimers on the cleavage processes of the peptide GHK and its analogues

Fragmentation mechanisms of the singly protonated peptides GHK, GHKH and HGHK have been investigated by mass spectrometry and theoretical calculations. Fragmentation behavior of the protonated H–K amide bond in GHK was changed completely when a histidinyl residue was introduced into the C-terminus o...

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Detalles Bibliográficos
Autores principales: Wang, Jinhu, Wang, Cheng, Zhang, Han, Liu, Yang, Shi, Tiesheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694339/
https://www.ncbi.nlm.nih.gov/pubmed/35424374
http://dx.doi.org/10.1039/d0ra07600g