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HSA-Lys-161 covalent bound fluorescent dye for in vivo blood drug dynamic imaging and tumor mapping

The specific combination of human serum albumin and fluorescent dye will endow superior performance to a coupled fluorescent platform for in vivo fluorescence labeling. In this study, we found that lysine-161 in human serum albumin is a covalent binding site and could spontaneously bind a ketone ske...

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Detalles Bibliográficos
Autores principales: Yue, Yongkang, Zhao, Tingting, Wang, Yuting, Ma, Kaiqing, Wu, Xingkang, Huo, Fangjun, Cheng, Fangqin, Yin, Caixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694392/
https://www.ncbi.nlm.nih.gov/pubmed/35059170
http://dx.doi.org/10.1039/d1sc05484h