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Expansion of invariant natural killer T cells from systemic lupus erythematosus patients by alpha-Galactosylceramide and IL-15

CD1d-restricted invariant natural killer T cells (iNKT cells) may play an important role in the pathogenesis of systemic lupus erythematosus (SLE). Interleukin (IL)-15 is a pro-inflammatory cytokine which is over-expressed in SLE patients. In the present study, we investigated the iNKT cell expansio...

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Detalles Bibliográficos
Autores principales: Hsu, Chien-Ya, Chueh, Yu-Shan, Kuo, Ming-Ling, Lee, Pei-Tzu, Hsiao, Hsiu-Shan, Huang, Jing-Long, Lin, Syh-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694473/
https://www.ncbi.nlm.nih.gov/pubmed/34936686
http://dx.doi.org/10.1371/journal.pone.0261727