Platelet microRNAs inhibit primary tumor growth via broad modulation of tumor cell mRNA expression in ectopic pancreatic cancer in mice

We investigated the contributions of platelet microRNAs (miRNAs) to the rate of growth and regulation of gene expression in primary ectopic tumors using mouse models. We previously identified an inhibitory role for platelets in solid tumor growth, mediated by tumor infiltration of platelet microvesi...

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Detalles Bibliográficos
Autores principales: Wurtzel, Jeremy G. T., Lazar, Sophia, Sikder, Sonali, Cai, Kathy Q., Astsaturov, Igor, Weyrich, Andrew S., Rowley, Jesse W., Goldfinger, Lawrence E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694476/
https://www.ncbi.nlm.nih.gov/pubmed/34936674
http://dx.doi.org/10.1371/journal.pone.0261633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694476/
https://www.ncbi.nlm.nih.gov/pubmed/34936674
http://dx.doi.org/10.1371/journal.pone.0261633

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