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Platelet microRNAs inhibit primary tumor growth via broad modulation of tumor cell mRNA expression in ectopic pancreatic cancer in mice
We investigated the contributions of platelet microRNAs (miRNAs) to the rate of growth and regulation of gene expression in primary ectopic tumors using mouse models. We previously identified an inhibitory role for platelets in solid tumor growth, mediated by tumor infiltration of platelet microvesi...
Autores principales: | Wurtzel, Jeremy G. T., Lazar, Sophia, Sikder, Sonali, Cai, Kathy Q., Astsaturov, Igor, Weyrich, Andrew S., Rowley, Jesse W., Goldfinger, Lawrence E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694476/ https://www.ncbi.nlm.nih.gov/pubmed/34936674 http://dx.doi.org/10.1371/journal.pone.0261633 |
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