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Enhancing the biological activity of polyoxometalate–peptide nano-fibrils by spacer design

Polyoxometalates (POMs) and peptides can be conjugated to yield novel bio-hybrids with potential application as nanodrugs. However, the observed POM-induced folding of the peptide prevents its availability towards biological targets. An Anderson–Evans POM was functionalized with a bombesin analog pe...

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Detalles Bibliográficos
Autores principales: Tagliavini, Valeria, Honisch, Claudia, Serratì, Simona, Azzariti, Amalia, Bonchio, Marcella, Ruzza, Paolo, Carraro, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694496/
https://www.ncbi.nlm.nih.gov/pubmed/35424453
http://dx.doi.org/10.1039/d0ra10218k