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Metal-free synthesis of 1,4-benzodiazepines and quinazolinones from hexafluoroisopropyl 2-aminobenzoates at room temperature

Herein, we describe the novel reactivity of hexafluoroisopropyl 2-aminobenzoates. The metal-free synthesis of 1,4-benzodiazepines and quinazolinones from hexafluoroisopropyl 2-aminobenzoates has been developed at room temperature. These procedures feature good functional group tolerance, mild reacti...

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Detalles Bibliográficos
Autores principales: Chen, Jiewen, Liang, En, Shi, Jie, Wu, Yinrong, Wen, Kangmei, Yao, Xingang, Tang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694548/
https://www.ncbi.nlm.nih.gov/pubmed/35424458
http://dx.doi.org/10.1039/d1ra00324k