Angiotensin-(1–7) Analogue AVE0991 Modulates Astrocyte-Mediated Neuroinflammation via lncRNA SNHG14/miR-223-3p/NLRP3 Pathway and Offers Neuroprotection in a Transgenic Mouse Model of Alzheimer's Disease

OBJECTIVE: Emerging evidence suggests that brain angiotensin-(1–7) (Ang-(1–7)) deficiency contributes to the pathogenesis of Alzheimer’s disease (AD). Meanwhile, our previous studies revealed that restoration of brain Ang-(1–7) levels provided neuroprotection by inhibition of inflammatory responses...

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Detalles Bibliográficos
Autores principales: Duan, Rui, Wang, Si-Yu, Wei, Bin, Deng, Yang, Fu, Xin-Xin, Gong, Peng-Yu, E, Yan, Sun, Xiao-Jin, Cao, Hai-Ming, Shi, Jian-Quan, Jiang, Teng, Zhang, Ying-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694579/
https://www.ncbi.nlm.nih.gov/pubmed/34955647
http://dx.doi.org/10.2147/JIR.S343575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694579/
https://www.ncbi.nlm.nih.gov/pubmed/34955647
http://dx.doi.org/10.2147/JIR.S343575

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