Cryo-EM structure of the autoinhibited state of myosin-2

We solved the near-atomic resolution structure of smooth muscle myosin-2 in the autoinhibited state (10S) using single-particle cryo–electron microscopy. The 3.4-Å structure reveals the precise molecular architecture of 10S and the structural basis for myosin-2 regulation. We reveal the position of...

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Detalles Bibliográficos
Autores principales: Heissler, Sarah M., Arora, Amandeep S., Billington, Neil, Sellers, James R., Chinthalapudi, Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694606/
https://www.ncbi.nlm.nih.gov/pubmed/34936462
http://dx.doi.org/10.1126/sciadv.abk3273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694606/
https://www.ncbi.nlm.nih.gov/pubmed/34936462
http://dx.doi.org/10.1126/sciadv.abk3273

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