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The pH-triggered drug release and simultaneous carrier decomposition of effervescent SiO(2)–drug–Na(2)CO(3) composite nanoparticles: to improve the antitumor activity of hydrophobic drugs

To achieve a better release effect of hydrophobic drugs and spontaneous nanocarrier disintegration by dissolution as well as the CO(2) production of Na(2)CO(3) further, improving the therapeutic effect of hydrophobic drugs, and thereby avoiding the accumulation of the nanocarrier in vivo to produce...

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Detalles Bibliográficos
Autores principales: Chen, Tianyu, Jiang, Yichun, Wang, Changmao, Cai, Zhengxue, Chen, Hui, Zhu, Junliang, Tao, Pinrun, Wu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694630/
https://www.ncbi.nlm.nih.gov/pubmed/35423073
http://dx.doi.org/10.1039/d0ra07896d