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Identification of key lipid metabolites during metabolic dysregulation in the diabetic retinopathy disease mouse model and efficacy of Keluoxin capsule using an UHPLC-MS-based non-targeted lipidomics approach

Diabetic retinopathy (DR) is an important complication of diabetes, and is currently the main cause of blindness among young adults in the world. Previous studies have shown that Keluoxin (KLX) capsules have a significant effect on DR in C57BL/KsJ/db(−/−) mice (db/db mice), however the unclear mecha...

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Detalles Bibliográficos
Autores principales: Ge, Nan, Kong, Ling, Zhang, Ai-hua, Sun, Ye, Zhao, Man-qian, Zhang, Bo, Xu, Lei, Ke, Xiao, Sun, Hui, Wang, Xi-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694764/
https://www.ncbi.nlm.nih.gov/pubmed/35423075
http://dx.doi.org/10.1039/d0ra00343c