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Mechanistic study of nucleophilic fluorination for the synthesis of fluorine-18 labeled fluoroform with high molar activity from N-difluoromethyltriazolium triflate

The synthesis of fluorine-18 labeled fluoroform with high molar activity has grown in importance for the development of fluorine-18 labeled aryl-CF(3) radiopharmaceuticals that are useful as diagnostic radiotracers for the powerful technique of positron emission tomography (PET). We designed a strat...

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Detalles Bibliográficos
Autores principales: Chai, Jin Young, Cha, Hyojin, Lee, Sung-Sik, Oh, Young-Ho, Lee, Sungyul, Chi, Dae Yoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694808/
https://www.ncbi.nlm.nih.gov/pubmed/35423150
http://dx.doi.org/10.1039/d0ra09827b