Investigation of interactions between binding residues and solubility of grafted humanized anti-VEGF IgG antibodies expressed as full-length format in the cytoplasm of a novel engineered E. coli SHuffle strain

Monoclonal antibodies (mAbs) are one of the fastest-growing areas of biopharmaceutical industry and have been widely used for a broad spectrum of diseases. Meanwhile, the immunogenicity of non-human derived antibodies can generate side effects by inducing the human immune response to produce human a...

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Detalles Bibliográficos
Autores principales: Sangpheak, Kanyani, Waraho-zhmayev, Dujduan, Haonoo, Korakod, Torpaiboon, Sarun, Teacharsripaiboon, Tarin, Rungrotmongkol, Thanyada, Poo-arporn, Rungtiva P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694825/
https://www.ncbi.nlm.nih.gov/pubmed/35423148
http://dx.doi.org/10.1039/d0ra08534k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694825/
https://www.ncbi.nlm.nih.gov/pubmed/35423148
http://dx.doi.org/10.1039/d0ra08534k

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