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Solubility and biological activity enhancement of docetaxel via formation of inclusion complexes with three alkylenediamine-modified β-cyclodextrins

Docetaxel (DTX) is an effective and commonly used chemotherapeutic drug for cancer. However, its efficacy is greatly compromised because of its toxicity and poor water solubility. In order to overcome these disadvantages, three inclusion complexes between DTX and alkylenediamine-modified β-cyclodext...

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Detalles Bibliográficos
Autores principales: Chen, Xiang-Yu, Yang, Hui-Wen, Chi, Shao-Ming, Yue, Lu-Lu, Ruan, Qiong, Lei, Ze, Zhu, Hong-You, Zhao, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694830/
https://www.ncbi.nlm.nih.gov/pubmed/35423130
http://dx.doi.org/10.1039/d0ra09720a