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Synthesis of a DOTA-C-glyco bifunctional chelating agent and preliminary in vitro and in vivo study of [(68)Ga]Ga-DOTA-C-glyco-RGD

The design of bifunctional chelating agents (BFCA) allowing straightforward radiometal labelling of biomolecules is a current challenge. We report herein the development of a bifunctional chelating agent based on a DOTA chelator linked to a C-glycosyl compound, taking advantage of the robustness and...

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Detalles Bibliográficos
Autores principales: Mangin, Floriane, Collet, Charlotte, Jouan-Hureaux, Valérie, Maskali, Fatiha, Roeder, Emilie, Pierson, Julien, Selmeczi, Katalin, Marie, Pierre-Yves, Boura, Cédric, Pellegrini-Moïse, Nadia, Lamandé-Langle, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694941/
https://www.ncbi.nlm.nih.gov/pubmed/35423261
http://dx.doi.org/10.1039/d0ra09274f