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Palladium catalyzed reductive Heck coupling and its application in total synthesis of (−)-17-nor-excelsinidine

Monoterpene indole alkaloids, bearing a highly substituted piperidine ring, are a structurally diverse class of bioactive natural products, found in various parts of the world. Herein, we reported the construction of the key piperidine ring via palladium catalyzed reductive Heck coupling with a good...

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Detalles Bibliográficos
Autores principales: Yuan, Lisi, Chen, Linrong, Yan, Xiaoxiao, Gao, Kun, Wang, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694955/
https://www.ncbi.nlm.nih.gov/pubmed/35423278
http://dx.doi.org/10.1039/d1ra00015b