SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans

SARS-CoV-2 mRNA vaccines induce robust anti-spike (S) antibody and CD4(+) T cell responses. It is not yet clear whether vaccine-induced follicular helper CD4(+) T (T(FH)) cell responses contribute to this outstanding immunogenicity. Using fine-needle aspiration of draining axillary lymph nodes from...

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Detalles Bibliográficos
Autores principales: Mudd, Philip A., Minervina, Anastasia A., Pogorelyy, Mikhail V., Turner, Jackson S., Kim, Wooseob, Kalaidina, Elizaveta, Petersen, Jan, Schmitz, Aaron J., Lei, Tingting, Haile, Alem, Kirk, Allison M., Mettelman, Robert C., Crawford, Jeremy Chase, Nguyen, Thi H.O., Rowntree, Louise C., Rosati, Elisa, Richards, Katherine A., Sant, Andrea J., Klebert, Michael K., Suessen, Teresa, Middleton, William D., Wolf, Joshua, Teefey, Sharlene A., O’Halloran, Jane A., Presti, Rachel M., Kedzierska, Katherine, Rossjohn, Jamie, Thomas, Paul G., Ellebedy, Ali H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695127/
https://www.ncbi.nlm.nih.gov/pubmed/35026152
http://dx.doi.org/10.1016/j.cell.2021.12.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695127/
https://www.ncbi.nlm.nih.gov/pubmed/35026152
http://dx.doi.org/10.1016/j.cell.2021.12.026

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