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SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans
SARS-CoV-2 mRNA vaccines induce robust anti-spike (S) antibody and CD4(+) T cell responses. It is not yet clear whether vaccine-induced follicular helper CD4(+) T (T(FH)) cell responses contribute to this outstanding immunogenicity. Using fine-needle aspiration of draining axillary lymph nodes from...
Autores principales: | Mudd, Philip A., Minervina, Anastasia A., Pogorelyy, Mikhail V., Turner, Jackson S., Kim, Wooseob, Kalaidina, Elizaveta, Petersen, Jan, Schmitz, Aaron J., Lei, Tingting, Haile, Alem, Kirk, Allison M., Mettelman, Robert C., Crawford, Jeremy Chase, Nguyen, Thi H.O., Rowntree, Louise C., Rosati, Elisa, Richards, Katherine A., Sant, Andrea J., Klebert, Michael K., Suessen, Teresa, Middleton, William D., Wolf, Joshua, Teefey, Sharlene A., O’Halloran, Jane A., Presti, Rachel M., Kedzierska, Katherine, Rossjohn, Jamie, Thomas, Paul G., Ellebedy, Ali H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695127/ https://www.ncbi.nlm.nih.gov/pubmed/35026152 http://dx.doi.org/10.1016/j.cell.2021.12.026 |
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