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Improved herbicide discovery using physico-chemical rules refined by antimalarial library screening
Herbicides have physico-chemical properties not unlike orally-delivered human drugs, but are known to diverge in their limits for proton donors, partition coefficients and molecular weight. To further refine rules specific for herbicides, we exploited the close evolutionary relationship between Plas...
Autores principales: | Sukhoverkov, Kirill V., Corral, Maxime G., Leroux, Julie, Haywood, Joel, Johnen, Philipp, Newton, Trevor, Stubbs, Keith A., Mylne, Joshua S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695207/ https://www.ncbi.nlm.nih.gov/pubmed/35423398 http://dx.doi.org/10.1039/d1ra00914a |
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