MLH1 mediates cytoprotective nucleophagy to resist 5-Fluorouracil-induced cell death in colorectal carcinoma

Colorectal Cancer (CRC) with Microsatellite instability (MSI) and mutLhomolog-1 (MLH1) gene deficiency are less aggressive than MLH1 proficient cancers. MLH1 is involved in several cellular processes, but its connection with the autophagy-dependent cellular response towards anticancer drugs remains...

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Detalles Bibliográficos
Autores principales: Manzoor, Shaista, Saber-Ayad, Maha, Maghazachi, Azzam A., Hamid, Qutayba, Muhammad, Jibran Sualeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695220/
https://www.ncbi.nlm.nih.gov/pubmed/34952246
http://dx.doi.org/10.1016/j.neo.2021.12.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695220/
https://www.ncbi.nlm.nih.gov/pubmed/34952246
http://dx.doi.org/10.1016/j.neo.2021.12.003

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