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MLH1 mediates cytoprotective nucleophagy to resist 5-Fluorouracil-induced cell death in colorectal carcinoma

Colorectal Cancer (CRC) with Microsatellite instability (MSI) and mutLhomolog-1 (MLH1) gene deficiency are less aggressive than MLH1 proficient cancers. MLH1 is involved in several cellular processes, but its connection with the autophagy-dependent cellular response towards anticancer drugs remains...

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Detalles Bibliográficos
Autores principales:	Manzoor, Shaista, Saber-Ayad, Maha, Maghazachi, Azzam A., Hamid, Qutayba, Muhammad, Jibran Sualeh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695220/ https://www.ncbi.nlm.nih.gov/pubmed/34952246 http://dx.doi.org/10.1016/j.neo.2021.12.003

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