Structural alterations in the catalytic core of hSIRT2 enzyme predict therapeutic benefits of Garcinia mangostana derivatives in Alzheimer's disease: molecular dynamics simulation study

Recent studies have shown that inhibition of the hSIRT2 enzyme provides favorable effects in neurodegenerative diseases such as Alzheimer's disease. Prenylated xanthone phytochemicals including α-mangostin, β-mangostin and γ-mangostin obtained from Garcinia mangostana, a well-established tropic...

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Detalles Bibliográficos
Autores principales: Akawa, Oluwole B., Subair, Temitayo I., Soremekun, Opeyemi S., Olotu, Fisayo A., Soliman, Mahmoud E. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695224/
https://www.ncbi.nlm.nih.gov/pubmed/35423339
http://dx.doi.org/10.1039/d0ra10459k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695224/
https://www.ncbi.nlm.nih.gov/pubmed/35423339
http://dx.doi.org/10.1039/d0ra10459k

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