The antimicrobial peptide LL-37 triggers release of apoptosis-inducing factor and shows direct effects on mitochondria

The human antimicrobial peptide LL-37 permeabilizes the plasma membrane of host cells, but LL-37-induced direct effects on mitochondrial membrane permeability and function has not been reported. Here, we demonstrate that LL-37 is rapidly (within 20 min) internalized by human osteoblast-like MG63 cel...

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Detalles Bibliográficos
Autores principales: Bankell, Elisabeth, Liu, Xiaoyan, Lundqvist, Martin, Svensson, Daniel, Swärd, Karl, Sparr, Emma, Nilsson, Bengt-Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695256/
https://www.ncbi.nlm.nih.gov/pubmed/34988298
http://dx.doi.org/10.1016/j.bbrep.2021.101192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695256/
https://www.ncbi.nlm.nih.gov/pubmed/34988298
http://dx.doi.org/10.1016/j.bbrep.2021.101192

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