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Integrative molecular analysis of combined small-cell lung carcinomas identifies major subtypes with different therapeutic opportunities

BACKGROUND: Combined small-cell lung cancer (C-SCLC) is composed of SCLC admixed with a non-small-cell cancer component. They currently receive the same treatment as SCLC. The recent evidence that SCLC may belong to either of two lineages, neuroendocrine (NE) or non-NE, with different vulnerability...

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Detalles Bibliográficos
Autores principales: Simbolo, M., Centonze, G., Ali, G., Garzone, G., Taormina, S., Sabella, G., Ciaparrone, C., Mafficini, A., Grillo, F., Mangogna, A., Volante, M., Mastracci, L., Fontanini, G., Pilotto, S., Bria, E., Infante, M., Capella, C., Rolli, L., Pastorino, U., Milella, M., Milione, M., Scarpa, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695295/
https://www.ncbi.nlm.nih.gov/pubmed/34952268
http://dx.doi.org/10.1016/j.esmoop.2021.100308