Considering both small and large scale motions of vascular endothelial growth factor (VEGF) is crucial for reliably predicting its binding affinities to DNA aptamers

Vascular endothelial growth factor 165 (VEGF(165)), a predominant isoform of VEGF signal proteins, is an ideal target for developing drugs against various diseases. It is composed of a heparin binding domain (HBD) and a receptor binding domain (RBD), which are connected by a flexible linker. Among t...

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Detalles Bibliográficos
Autores principales: Lee, Wook, Park, Jae Whee, Go, Yeon Ju, Kim, Won Jong, Rhee, Young Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695334/
https://www.ncbi.nlm.nih.gov/pubmed/35423456
http://dx.doi.org/10.1039/d0ra10106k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695334/
https://www.ncbi.nlm.nih.gov/pubmed/35423456
http://dx.doi.org/10.1039/d0ra10106k

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