Total synthesis of landomycins Q and R and related core structures for exploration of the cytotoxicity and antibacterial properties

Herein, we report the total synthesis of landomycins Q and R as well as the aglycone core, namely anhydrolandomycinone and a related core analogue. The synthesis features an acetate-assisted arylation method for construction of the hindered B-ring in the core component and a one-pot aromatization–de...

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Detalles Bibliográficos
Autores principales: Lai, Yao-Hsuan, Mondal, Soumik, Su, Hsin-Tzu, Huang, Sheng-Cih, Wu, Mine-Hsine, Huang, I.-Wen, Yang Lauderdale, Tsai-Ling, Song, Jen-Shin, Shia, Kak-Shan, Mong, Kwok-Kong Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695357/
https://www.ncbi.nlm.nih.gov/pubmed/35423459
http://dx.doi.org/10.1039/d1ra01088c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695357/
https://www.ncbi.nlm.nih.gov/pubmed/35423459
http://dx.doi.org/10.1039/d1ra01088c

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