Cargando…

ROS-responsive nanoparticle-mediated delivery of CYP2J2 gene for therapeutic angiogenesis in severe hindlimb ischemia

With critical limb ischemia (CLI) being a multi-factorial disease, it is becoming evident that gene therapy with a multiple bio-functional growth factor could achieve better therapeutic outcomes. Cytochrome P450 epoxygenase-2J2 (CYP2J2) and its catalytic products epoxyeicosatrienoic acids (EETs) exh...

Descripción completa

Detalles Bibliográficos
Autores principales: Gui, Liang, Chen, Youlu, Diao, Yongpeng, Chen, Zuoguan, Duan, Jianwei, Liang, Xiaoyu, Li, Huiyang, Liu, Kaijing, Miao, Yuqing, Gao, Qing, Li, Zhichao, Yang, Jing, Li, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695365/
https://www.ncbi.nlm.nih.gov/pubmed/34988419
http://dx.doi.org/10.1016/j.mtbio.2021.100192