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FABP4 activates the JAK2/STAT2 pathway via Rap1a in the homocysteine-induced macrophage inflammatory response in ApoE(−/−) mice atherosclerosis

Atherosclerosis is a chronic inflammatory vascular disease, and inflammation plays a critical role in its formation and progression. Elevated serum homocysteine (Hcy) is an independent risk factor for atherosclerosis. Previous studies have shown that fatty acid binding protein 4 (FABP4) plays an imp...

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Detalles Bibliográficos
Autores principales: Xu, Lingbo, Zhang, Huiping, Wang, Yanhua, Yang, Anning, Dong, Xiaoyan, Gu, Lingyu, Liu, Dayue, Ding, Ning, Jiang, Yideng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695379/
https://www.ncbi.nlm.nih.gov/pubmed/34725437
http://dx.doi.org/10.1038/s41374-021-00679-2