A conserved mechanism for regulating replisome disassembly in eukaryotes

Replisome disassembly is the final step of eukaryotic DNA replication and is triggered by ubiquitylation of the CDC45–MCM–GINS (CMG) replicative helicase(1–3). Despite being driven by evolutionarily diverse E3 ubiquitin ligases in different eukaryotes (SCF(Dia2) in budding yeast(1), CUL2(LRR1) in me...

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Detalles Bibliográficos
Autores principales: Jenkyn-Bedford, Michael, Jones, Morgan L., Baris, Yasemin, Labib, Karim P. M., Cannone, Giuseppe, Yeeles, Joseph T. P., Deegan, Tom D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695382/
https://www.ncbi.nlm.nih.gov/pubmed/34700328
http://dx.doi.org/10.1038/s41586-021-04145-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695382/
https://www.ncbi.nlm.nih.gov/pubmed/34700328
http://dx.doi.org/10.1038/s41586-021-04145-3

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