Biologically guided isolation and ADMET profile of new factor Xa inhibitors from Glycyrrhiza glabra roots using in vitro and in silico approaches

Selective factor Xa inhibitors effectively block coagulation cascade with a broader therapeutic window than multitargeted anticoagulants. They have evolved as a crucial part of prevention and treatment of thromboembolic diseases and in therapeutic protocols involved in many clinical trials in corona...

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Detalles Bibliográficos
Autores principales: Ibrahim, Reham S., Mahrous, Rahma S. R., Abu EL-Khair, Rasha M., Ross, Samir A., Omar, Abdallah A., Fathy, Hoda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695410/
https://www.ncbi.nlm.nih.gov/pubmed/35423517
http://dx.doi.org/10.1039/d1ra00359c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695410/
https://www.ncbi.nlm.nih.gov/pubmed/35423517
http://dx.doi.org/10.1039/d1ra00359c

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