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Contingent intramuscular boosting of P2XR7 axis improves motor function in transgenic ALS mice

Amyotrophic lateral sclerosis is a fatal neurodegenerative disorder that leads to progressive degeneration of motor neurons and severe muscle atrophy without effective treatment. Most research on the disease has been focused on studying motor neurons and supporting cells of the central nervous syste...

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Detalles Bibliográficos
Autores principales: Fabbrizio, Paola, D’Agostino, Jessica, Margotta, Cassandra, Mella, Giulia, Panini, Nicolò, Pasetto, Laura, Sammali, Eliana, Raggi, Flavia, Sorarù, Gianni, Bonetto, Valentina, Bendotti, Caterina, Nardo, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695421/
https://www.ncbi.nlm.nih.gov/pubmed/34936028
http://dx.doi.org/10.1007/s00018-021-04070-8