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Contingent intramuscular boosting of P2XR7 axis improves motor function in transgenic ALS mice
Amyotrophic lateral sclerosis is a fatal neurodegenerative disorder that leads to progressive degeneration of motor neurons and severe muscle atrophy without effective treatment. Most research on the disease has been focused on studying motor neurons and supporting cells of the central nervous syste...
Autores principales: | Fabbrizio, Paola, D’Agostino, Jessica, Margotta, Cassandra, Mella, Giulia, Panini, Nicolò, Pasetto, Laura, Sammali, Eliana, Raggi, Flavia, Sorarù, Gianni, Bonetto, Valentina, Bendotti, Caterina, Nardo, Giovanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695421/ https://www.ncbi.nlm.nih.gov/pubmed/34936028 http://dx.doi.org/10.1007/s00018-021-04070-8 |
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