Circadian Influences on Chemotherapy Efficacy in a Mouse Model of Brain Metastases of Breast Cancer

Chemotherapy is more effective in the treatment of peripheral tumors than brain metastases, likely reflecting the reduced ability of chemotherapy to cross the blood-brain barrier (BBB) and blood-tumor barrier at efficacious concentrations. Recent studies demonstrate circadian regulation of the BBB....

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Detalles Bibliográficos
Autores principales: Walker, William H., Sprowls, Samuel A., Bumgarner, Jacob R., Liu, Jennifer A., Meléndez-Fernández, O. Hecmarie, Walton, James C., Lockman, Paul R., DeVries, A. Courtney, Nelson, Randy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695439/
https://www.ncbi.nlm.nih.gov/pubmed/34956876
http://dx.doi.org/10.3389/fonc.2021.752331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695439/
https://www.ncbi.nlm.nih.gov/pubmed/34956876
http://dx.doi.org/10.3389/fonc.2021.752331

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