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Impact of NK Cell Activating Receptor Gene Variants on Receptor Expression and Outcome of Immunotherapy in Acute Myeloid Leukemia

Natural killer cells are important effector cells in the immune response against myeloid malignancies. Previous studies show that the expression of activating NK cell receptors is pivotal for efficient recognition of blasts from patients with acute myeloid leukemia (AML) and that high expression lev...

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Detalles Bibliográficos
Autores principales: Hussein, Brwa Ali, Hallner, Alexander, Wennström, Lovisa, Brune, Mats, Martner, Anna, Hellstrand, Kristoffer, Bernson, Elin, Thorén, Fredrik B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695486/
https://www.ncbi.nlm.nih.gov/pubmed/34956230
http://dx.doi.org/10.3389/fimmu.2021.796072