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Alternative tissue fixation for combined histopathological and molecular analysis in a clinically representative setting

Formalin is the principal tissue fixative used worldwide for clinical and research purposes. Despite optimal preservation of morphology, its preservation of DNA and RNA is poor. As clinical diagnostics increasingly incorporates molecular-based analysis, the requirement for maintaining nucleic acid q...

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Detalles Bibliográficos
Autores principales: Meecham, Amelia, Miranda, Elena, Morris, Hayley T., Hair, Jane, Oien, Karin A., Gerrard, Gareth, Guppy, Naomi, Mooney, David, Shaw, Emily C., Ashton-Key, Margaret, Lees, Robert, Flanagan, Adrienne, Rodriguez-Justo, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695534/
https://www.ncbi.nlm.nih.gov/pubmed/34905068
http://dx.doi.org/10.1007/s00418-021-02029-1