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DNA/RNA heteroduplex oligonucleotide technology for regulating lymphocytes in vivo

Manipulating lymphocyte functions with gene silencing approaches is promising for treating autoimmunity, inflammation, and cancer. Although oligonucleotide therapy has been proven to be successful in treating several conditions, efficient in vivo delivery of oligonucleotide to lymphocyte populations...

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Detalles Bibliográficos
Autores principales: Ohyagi, Masaki, Nagata, Tetsuya, Ihara, Kensuke, Yoshida-Tanaka, Kie, Nishi, Rieko, Miyata, Haruka, Abe, Aya, Mabuchi, Yo, Akazawa, Chihiro, Yokota, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695577/
https://www.ncbi.nlm.nih.gov/pubmed/34937876
http://dx.doi.org/10.1038/s41467-021-26902-8