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The bacterial promoter spacer modulates promoter strength and timing by length, TG-motifs and DNA supercoiling sensitivity

Transcription, the first step to gene expression, is a central coordination process in all living matter. Besides a plethora of regulatory mechanisms, the promoter architecture sets the foundation of expression strength, timing and the potential for further regulatory modulation. In this study, we i...

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Detalles Bibliográficos
Autores principales: Klein, Carlo A., Teufel, Marc, Weile, Carl J., Sobetzko, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695583/
https://www.ncbi.nlm.nih.gov/pubmed/34937877
http://dx.doi.org/10.1038/s41598-021-03817-4