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The bacterial promoter spacer modulates promoter strength and timing by length, TG-motifs and DNA supercoiling sensitivity
Transcription, the first step to gene expression, is a central coordination process in all living matter. Besides a plethora of regulatory mechanisms, the promoter architecture sets the foundation of expression strength, timing and the potential for further regulatory modulation. In this study, we i...
Autores principales: | Klein, Carlo A., Teufel, Marc, Weile, Carl J., Sobetzko, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695583/ https://www.ncbi.nlm.nih.gov/pubmed/34937877 http://dx.doi.org/10.1038/s41598-021-03817-4 |
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