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Discovery and characterization of naturally occurring potent inhibitors of catechol-O-methyltransferase from herbal medicines
Human catechol-O-methyltransferase (hCOMT) is considered a therapeutic target due to its crucial roles in the metabolic inactivation of endogenous neurotransmitters and xenobiotic drugs. There are nevertheless few safe and effective COMT inhibitors and there lacks a diversity in structure. To discov...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695704/ https://www.ncbi.nlm.nih.gov/pubmed/35423513 http://dx.doi.org/10.1039/d0ra10425f |