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Synergistic Combination of Facile Thiol-Maleimide Derivatization and Supramolecular Solvent-Based Microextraction for UHPLC–HRMS Analysis of Glutathione in Biofluids

Glutathione (GSH) is the most abundant non-protein thiol in biofluids, enabling diverse physiological functions. Among the proposed methods for GSH detection, ultra-high-performance liquid chromatography (UHPLC) coupled with high-resolution mass spectrometry (HRMS) has the advantages of high sensiti...

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Detalles Bibliográficos
Autores principales: Yan, Mengmeng, Gao, Feng, Chen, Meng, Hu, Qi, Yang, Yuqin, Chen, Kedian, Wang, Penglong, Lei, Haimin, Ma, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695729/
https://www.ncbi.nlm.nih.gov/pubmed/34957048
http://dx.doi.org/10.3389/fchem.2021.786627